ETO Indicating Labels

Sterile indicating labels for quality assurance

Elevate the safety and reliability of your sterilization processes with our ETO Indicating Labels, engineered to provide visual confirmation of successful ethylene oxide sterilization. Trusted across healthcare, pharmaceutical, and medical device industries, our ETO Indicating Labels offer a vital tool for ensuring product safety and adherence to the highest industry standards.

Quickly find the perfect labels for your needs.

Product Information

Explore how our labels can satisfy your requirements

ETO indicating labels are a game-changer in sterilization monitoring, offering a cutting-edge solution for various industries. These labels seamlessly incorporate advanced ethylene oxide (ETO) indicating ink within their design. This innovative ink can be applied as text or shapes, allowing for unmatched flexibility in label placement. Whether it's branding, barcodes, or lot information, our ETO indicating labels effortlessly integrate essential printed elements, resulting in enhanced packaging design and visually striking presentation.

What sets our ETO indicating labels apart is their direct application of ETO indicating ink, eliminating the labor-intensive process of manually applying indicators. This not only boosts efficiency but also translates into significant time and cost savings for your operations. Discover the advantages of our ETO indicating labels as they offer a streamlined and cost-effective packaging solution across diverse industries, ensuring sterilization integrity and safety.

  • Ethylene Oxide Sensitivity: ETO indicating labels are designed to be sensitive to ethylene oxide gas, a sterilant commonly used for the low-temperature sterilization of heat-sensitive medical devices and equipment. They change color or provide a visual indication when exposed to ETO gas.
  • Immediate Response: These labels offer a near-instantaneous visual response to the sterilization process, allowing users to quickly assess whether the ETO cycle has achieved proper sterilization conditions.
  • Passive Operation: ETO indicating labels are passive indicators that do not require external power sources or equipment for operation. They provide a straightforward and cost-effective means of monitoring ETO sterilization.
  • Permanent Record: The color change or visual indication on ETO indicating labels is often permanent, providing a long-term record that the sterilization process has been successfully completed.
  • Dose-Response Relationship: ETO indicating labels are designed to have a known and predictable dose-response relationship, enabling users to verify that the sterilization parameters have been met based on the extent of color change or visual indication.
  • Self-Adhesive: ETO indicating labels are typically self-adhesive, making them easy to apply to various surfaces, including packaging materials, autoclave bags, or sterilization containers.
  • ETO Exposure Range: ETO indicating labels are available in various exposure range options to cover different ETO sterilization processes, from low-dose cycles to high-dose cycles.
  • Adhesive Type: Customers have the option to choose from different adhesive types, including permanent adhesives or removable adhesives, depending on their specific labeling needs.
  • Color and Finish: Labels may come in different colors and finishes (e.g., matte or glossy) to accommodate specific labeling requirements, including color-coding or visual identification.
  • Barcode and QR Code Printing: ETO indicating labels can offer the option to print barcodes, QR codes, or other data matrix codes for inventory management, tracking, and traceability purposes.
  • Custom Printing: Customers can order custom-printed ETO indicating labels with specific information, such as sample details, storage conditions, and identification data.
  • Variable Data Printing: Labels can be customized with variable data printing, allowing for unique information on each label, such as sample identifiers, lot numbers, or expiration dates.
  • Print Method Compatibility: We can make ETO indicating labels that are compatible with thermal transfer printers, laser printers, and inkjet printers.
  • Size and Shape: ETO indicating labels may come in various sizes and shapes to accommodate different labeling needs and surfaces.
  • Healthcare and Medical Settings: ETO indicating labels are commonly used in hospitals, clinics, and healthcare facilities to monitor the sterilization of heat-sensitive medical instruments, surgical equipment, and devices that cannot withstand high-temperature sterilization methods.
  • Pharmaceutical Manufacturing: Pharmaceutical companies utilize ETO indicating labels to verify the sterilization of pharmaceutical products, packaging materials, and production equipment, ensuring product safety and quality.
  • Laboratories: Research laboratories and scientific facilities use ETO indicating labels to validate the sterilization of laboratory equipment and materials that are sensitive to heat, such as plasticware and certain chemicals.
  • Manufacturing of Optical and Precision Instruments: Optical and precision instrument manufacturers use ETO indicating labels to monitor and verify the sterilization of delicate optical devices, lenses, and precision instruments.
  • Quality Control and Compliance: ETO indicating labels play a crucial role in quality control and compliance with regulatory standards, ensuring that ETO sterilization cycles meet established parameters.
  • Research and Development: ETO indicating labels may be used in research and development projects involving the development and testing of new sterilization methods and techniques for heat-sensitive items.

1. What are ETO indicating labels?

ETO indicating labels are adhesive labels that change color when exposed to ethylene oxide gas during the ETO sterilization process. They provide a visual indication that an item has been subjected to ETO sterilization.

2. Why are ETO indicating labels used?

These labels help verify that medical equipment, pharmaceutical products, and other sensitive items have been exposed to ETO, ensuring adherence to sterilization protocols and maintaining safety standards.

3. How do ETO indicating labels work?

These labels contain a chemical dye that reacts specifically to the presence of ethylene oxide gas. The chemical reaction causes a noticeable color change in the label, indicating exposure to ETO.

4. Are ETO indicating labels reusable?

Unlike regular labels, cleanroom labels are processed and packaged in controlled environments to ensure they are free from contaminants. They also resist chemicals and extreme temperatures better.

5. What types of products are labeled with ETO indicating labels?

They are commonly used on medical devices, surgical instruments, and other products that require ETO sterilization, especially those sensitive to heat and moisture.

6. Can these labels indicate the effectiveness of the sterilization process?

While they confirm exposure to ETO, they do not directly measure the effectiveness of sterilization. They should be used as part of a comprehensive sterilization validation process.

7. How are ETO indicating labels applied?

They are typically applied to the product or its packaging before the sterilization process. The labels should be firmly attached to ensure accurate indication.

8. Can these labels withstand other forms of sterilization?

ETO indicating labels are specifically designed for ethylene oxide sterilization. Using them with other sterilization methods may not yield accurate indications.

9. How should products with ETO indicating labels be stored?

Store them in a cool, dry place, away from direct sunlight and extreme temperatures, to maintain their effectiveness until use.

10. Are there regulatory standards for using ETO indicating labels?

In the healthcare and pharmaceutical industries, there may be specific regulations and guidelines for sterilization processes, including the use of indicators like ETO labels. Ensure compliance with these standards when using such labels.

Why Choose CleanMark

Quality, Customization, and Speed at Your Service


Expert Guidance

Get the perfect label solution with advice from our team. We’re here to help every step of the way.


Custom Solutions

Drawing on extensive experience and diverse material options, we create labels that are tailor-made for you.


Seamless Integration

Set up your labels quickly and easily. They’re designed to fit right into your printing and application systems.


Swift Production

Need labels fast? Count on us for quick 4-day delivery, even for complex orders.


Adaptive Scalability

Your business changes, and so can your labels. We can easily adjust designs and production as you grow.

Why Choose CleanMark

Quality, Customization, and Speed at Your Service

Precision in Every Dimension

Our Label Design Process Focuses On 3 Key Areas


We assess and select the optimal adhesive to ensure reliable bonding and removal suited to a range of substrates and application scenarios.


Our design process involves optimizing release and peel values for seamless integration with both manual and machine applied label processes.


We ensure compatibility with your printing systems and application conditions so that your labels remain legible over time.


Find the Right
ETO Indicating Labels

Evaluate our label samples in your environment to assess their performance under your specific conditions. This will help you feel sure about choosing the right labels for your needs. We have many kinds of labels and can send you samples quickly to help you decide.

Additional options for ETO Indicating Labels

ETO Dots

ETO dots are compact, color-responsive indicators specifically designed to confirm exposure to ethylene oxide, commonly used in medical sterilization processes.

ETO Dots

ETO dots are compact, color-responsive indicators specifically designed to confirm exposure to ethylene oxide, commonly used in medical sterilization processes.

What Our Customers Say


"The CleanMark team was informative about the different materials and print processes. They were able to quickly get me samples to test as well as pre-production proofs to verify label size, orientation and color. They fulfilled on their promise to decrease my delivery time while improving print quality."

Ernie Schrepfer

Associate Director of Quality at Access Biologicals